TODAY今日发布CirculationJan28,:(4)今日发布15篇StrokeFeb01,:51(2)今日发布76篇StrokeEarlyRecent,Jan28,今日发布04篇JAHAFeb04,:9(3)今日发布05篇（共计22篇）TheLancetDigitalHealthFeb01,:2(2),e49-e今日发布13篇PediatricTransplantationEarlyRecent,Jan27,今日发布04篇ResearchandPracticeinThrombosisandHaemostasisEarlyRecent,Jan27,今日发布02篇RECOMMEND推荐阅读01作为心血管疾病发病率和死亡率关键危险因素的缺陷累积：对人的汇总分析JAHAresearch-articleMohammedA.M.Farooqi,HertzelGerstein,etc.1小时前等38用户推荐阅读本文BackgroundFrailtyisassociatedwithhighermortalityinindividualsathighcardiovasculardisease(CVD)risk.WehypothesizethatfrailtyisamoreimportantprognosticfactorthanCVDriskfactorsandaimtodeterminetheprognosticvalueofacumulativedeficitfrailtyindexinpatientswithorathighriskforCVD.在心血管疾病高危人群中，虚弱与较高的死亡率相关。我们假设脆弱性是比心血管病危险因素更重要的预后因素，并旨在确定累积缺陷脆弱性指数对心血管病患者或高危患者的预后价值。MethodsandResultsWeconductedanindividual‐levelpooledanalysisofparticipantswithoratriskforCVD,recruitedin14multicenterclinicaltrials.Thecumulativedeficitindexwascalculatedastheproportionof26deficitsexhibited.Individualswerecategorizedasnonfrail,prefrail,orfrailiftheyhadindexesof≤0.1,0.1to0.21,or0.21,respectively.CVDriskwasassessedusingtheFraminghamscore.Out
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